This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
A single published case report documents worsening of pemphigus, an autoantibody-driven blistering disease, in a patient after ingesting Phellinus linteus. It is the most serious adverse event linked to meshima anywhere in the literature.
Why it matters
It is the only human report that turns the theoretical concern about immunostimulants in autoimmune disease into something documented for this specific mushroom. A single case cannot establish causation or quantify risk, but it is the reason autoimmune caution for meshima is not purely hypothetical.
The numbers in context
One patient. No dose, duration or rechallenge data reported in the correspondence format.
How the study worked
Single-patient case report published as correspondence.
Who was studied
One patient with pemphigus.
What this study cannot tell us
n=1. Case reports cannot establish causation, cannot quantify risk magnitude, and are subject to publication bias. No rechallenge was performed and confounding exposures cannot be excluded.
Read the original research
Exacerbation of pemphigus following Phellinus linteus ingestion.
Journal of the European Academy of Dermatology and Venereology, 25(4), 492-493
Citation
Jin, Seon Pil; Hong, Jong Soo; Chung, Jin Ho. (2011). Exacerbation of pemphigus following Phellinus linteus ingestion.. Journal of the European Academy of Dermatology and Venereology, 25(4), 492-493. https://doi.org/10.1111/j.1468-3083.2010.03746.x