Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression: The EPISODE Randomized Clinical Trial.

RTHM-022372026Mertens, Lea J; Koslowski, Michael; Betzler, Felix; Brand, Manuela; Evens, Ricarda; Kärtner, Laura; Jungaberle, Andrea; Jungaberle, Henrik; Majic, Tomislav; Schmitz, Christian N; Ströhle, Andreas; Scharf, Dennis; Spangemacher, Moritz; Wolff, Max; Assadi, Zahra; Bahri, Scharif; Becher, Lilith; Färber, Luca V; Kirchen, Niklas; Kulakova, Eugenia; Kunz, Linda; Meijer, Andy; Rohrmoser, Barbara; Wellek, Stefan; Berger, Moritz M; Gründer, Gerhard

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Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression: The EPISODE Randomized Clinical Trial.

JAMA psychiatry

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Mertens, Lea J; Koslowski, Michael; Betzler, Felix; Brand, Manuela; Evens, Ricarda; Kärtner, Laura; Jungaberle, Andrea; Jungaberle, Henrik; Majic, Tomislav; Schmitz, Christian N; Ströhle, Andreas; Scharf, Dennis; Spangemacher, Moritz; Wolff, Max; Assadi, Zahra; Bahri, Scharif; Becher, Lilith; Färber, Luca V; Kirchen, Niklas; Kulakova, Eugenia; Kunz, Linda; Meijer, Andy; Rohrmoser, Barbara; Wellek, Stefan; Berger, Moritz M; Gründer, Gerhard. (2026). Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression: The EPISODE Randomized Clinical Trial.. JAMA psychiatry. https://doi.org/10.1001/jamapsychiatry.2026.0132