This record provides bibliographic details and links to the original research. An editorial study breakdown is not available.
What the researchers found
CB1 and 5-HT2A receptors form functionally active heteromers in specific brain regions, with cross-antagonism between the two receptors.
Read the original research
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.
PLoS biology, 13(7), e1002194
Citation
Viñals, Xavier; Moreno, Estefanía; Lanfumey, Laurence; Cordomí, Arnau; Pastor, Antoni; de la Torre, Rafael; Gasperini, Paola; Navarro, Gemma; Howell, Lesley A; Pardo, Leonardo; Lluís, Carme; Canela, Enric I; McCormick, Peter J; Maldonado, Rafael; Robledo, Patricia. (2015). Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.. PLoS biology, 13(7), e1002194. https://doi.org/10.1371/journal.pbio.1002194