Psilocybin Biosynthesis: Pathway, Genetics & Evolution
Explore mushroom research and guides on psilocybin biosynthesis: pathway, genetics & evolution.
From Tryptophan to Psilocybin: The Enzymatic Journey
Mushrooms make psilocybin from tryptophan using four enzymes — PsiD, PsiH, PsiK, and PsiM. Here's the complete step-by-step pathway with all intermediates.
Psilocybin Horizontal Gene Transfer: A Cross-Species Story
Why do unrelated mushrooms like Psilocybe and Panaeolus all make psilocybin? Reynolds 2018 and Bradshaw 2024 explain the HGT story and ecological trigger.
How Mushrooms Make Psilocybin: The Biosynthetic Pathway
Mushrooms make psilocybin from one amino acid using four enzymes. Here's how the pathway works, why only certain species can do it, and what this means for medicine.