Psilocybin Pharmacology Fundamentals
Explore mushroom research and guides on psilocybin pharmacology fundamentals.
How Psilocybin Works: The Complete Pharmacology Guide
Psilocybin is a prodrug converted to psilocin, which binds to 5-HT2A receptors and disrupts brain networks. Here's what the science actually shows.
Psilocybin vs. Psilocin: Understanding the Active Compound
Psilocybin is a prodrug. Your body converts it to psilocin, which actually crosses into the brain. Here's the chemistry, PK timeline, and why it matters.
What Happens in Your Brain on Psilocybin?
Siegel 2024 quantified psilocybin's brain effects: 3x more disruption than methylphenidate. Here's what imaging shows during and after the experience.