Psilocybin for Treatment-Resistant Depression
Explore mushroom research and guides on psilocybin for treatment-resistant depression.
How Psilocybin Helps When Antidepressants Fail
Psilocybin reaches patients SSRIs can't: a different mechanism, faster onset, and reversal of emotional blunting. Here's what the brain research shows.
Psilocybin for Treatment-Resistant Depression
Clinical trials show psilocybin produces 37% response and 29% remission in treatment-resistant depression patients who failed two or more antidepressants.
COMPASS Psilocybin Trial: The Complete Phase IIb Results
COMPASS Phase IIb tested psilocybin in 233 TRD patients across 22 sites. Here's what the data found, including the dose that failed and the durability gap.