β-Glucans are involved in immune-modulation of THP-1 macrophages.
Chanput, Wasaporn; Reitsma, Marit; Kleinjans, Lennart; Mes, Jurriaan J; Savelkoul, Huub F J; Wichers, Harry J ·
Research library — page 47
Browse more mushroom research, methods and limitations.
Oral administration of soluble β-glucans extracted from Grifola frondosa induces systemic antitumor immune response and decreases immunosuppression in tumor-bearing mice.
Masuda, Y; Inoue, H; Ohta, H; Miyake, A; Konishi, M; Nanba, H ·
Soluble β-glucan from Grifola frondosa induces tumor regression in synergy with TLR9 agonist via dendritic cell-mediated immunity.
Masuda, Y; Nawa, D; Nakayama, Y; Konishi, M; Nanba, H ·
Inhibitory effect of MD-Fraction on tumor metastasis: involvement of NK cell activation and suppression of intercellular adhesion molecule (ICAM)-1 expression in lung vascular endothelial cells.
Masuda, Y; Murata, Y; Hayashi, M; Nanba, H ·
The biological activities of the antitumor drug Grifola frondosa polysaccharide.
He, Y; Zhang, L; Wang, H ·
Immunomodulatory effects of lingzhi and san-miao-san supplementation on patients with rheumatoid arthritis.
Bao, Yi Xi; Wong, Chun Kwok; Li, Edmund Kwok Ming; Tam, Lai Shan; Leung, Ping Chung; Yin, Yi Bing; Lam, Christopher Wai Kei ·
Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial.
Li, Edmund K; Tam, Lai-Shan; Wong, Chun Kwok; Li, Wai Ching; Lam, Christopher W K; Wachtel-Galor, Sissi; Benzie, Iris F F; Bao, Yi Xi; Leung, Ping Chung; Tomlinson, Brian ·
Characterization and prediction of acute and sustained response to psychedelic psilocybin in a mindfulness group retreat.
Compared with placebo, psilocybin administered during a 5-day mindfulness retreat enhanced post-intervention mindfulness and produced larger positive changes in psychosocial functioning at a 4-month follow-up, corroborated by external ratings.
Smigielski, Lukasz; Kometer, Michael; Scheidegger, Milan; Krahenmann, Rainer; Huber, Theo; Vollenweider, Franz X · Randomized Controlled Trial
Tetrapolar fungal mating types: sexes by the thousands.
Kothe, E ·
Hypersensitivity pneumonitis induced by Shiitake mushroom spores.
Ampere, Alexandre; Delhaes, Laurence; Soots, Jacques; Bart, Frederic; Wallaert, Benoit ·
Fungal Sex: The Basidiomycota.
Coelho, Marco A; Bakkeren, Guus; Sun, Sheng; Hood, Michael E; Giraud, Tatiana ·
Modeling the consequences of the dikaryotic life cycle of mushroom-forming fungi on genomic conflict.
Auxier, Benjamin; Czárán, Tamás L; Aanen, Duur K ·
Live-cell imaging of septins and cell polarity proteins in the growing dikaryotic vegetative hypha of the model mushroom Coprinopsis cinerea.
Kakizaki, Tetsuya; Abe, Haruki; Kotouge, Yuuka; Matsubuchi, Mitsuki; Sugou, Mayu; Honma, Chiharu; Tsukuta, Kouki; Satoh, Souichi; Shioya, Tatsuhiro; Nakamura, Hiroe; Cannon, Kevin S; Woods, Benjamin L; Gladfelter, Amy; Takeshita, Norio; Muraguchi, Hajime ·
Insight into the nuclear distribution patterns of conidia and the asexual life cycle of Polyporus umbellatus.
Li, Shoujian; Li, Bing; Xu, Xinlei; Liu, Youyan; Xing, Yongmei; Guo, Shunxing ·
Treatment of cancer with mushroom products.
Monro, J A ·
Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients.
Gao, Yihuai; Zhou, Shufeng; Jiang, Wenqi; Huang, Min; Dai, Xihu ·
Enhanced MHC class I and costimulatory molecules on B16F10 cells by Ganoderma lucidum polysaccharides.
Sun, Li-Xin; Lin, Zhi-Bin; Duan, Xin-Suo; Lu, Jie; Ge, Zhi-Hua; Li, Xue-Fei; Li, Xue-Jun; Li, Min; Xing, En-Hong; Song, You-Xin; Jia, Jing; Li, Wei-Dong ·
Lanostane triterpenoids from Fomitopsis officinalis and their trypanocidal activity.
Naranmandakh, Shinen; Murata, Toshihiro; Odonbayar, Batsuren; Suganuma, Keisuke; Batkhuu, Javzan; Sasaki, Kenroh ·
Inhibition of cytochrome P450 isozymes in rat liver microsomes by polysaccharides derived from Phellinus linteus.
Phellinus linteus polysaccharides inhibited CYP1A1, CYP1A2, CYP2B1 and CYP2E1 activity in rat liver microsomes at 0.5-3 mg/ml. This is the only direct cytochrome P450 evidence for the mushroom, and it is an isolated-microsome result in a rat system, not a human drug-interaction study.
Shon, Yun Hee; Nam, Kyung Soo · In Vitro
Exacerbation of pemphigus following Phellinus linteus ingestion.
A single published case report documents worsening of pemphigus, an autoantibody-driven blistering disease, in a patient after ingesting Phellinus linteus. It is the most serious adverse event linked to meshima anywhere in the literature.
Jin, Seon Pil; Hong, Jong Soo; Chung, Jin Ho · Case Report
Optimized production and safety evaluation of hispidin-enriched Sanghuangporus sanghuang mycelia.
A standard four-assay toxicology battery (Ames test, in vitro chromosome aberration, acute oral toxicity, bone marrow micronucleus) on hispidin-enriched Sanghuangporus sanghuang mycelia found no statistically significant difference from negative controls, indicating a very low order of toxicity.
Li, I-Chen; Chen, Chin-Chu; Sheu, Shuenn-Jyi; Huang, I-Hsuan; Chen, Chien-Chih · Preclinical
In vitro and in vivo metabolism of psilocybin's active metabolite psilocin.
Thomann, Jan; Kolaczynska, Karolina E; Stoeckmann, Oliver V; Rudin, Deborah; Vizeli, Patrick; Hoener, Marius C; Pryce, Christopher R; Vollenweider, Franz X; Liechti, Matthias E; Duthaler, Urs ·
Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C19.
Koopmans, Anne B; Braakman, Mario H; Vinkers, David J; Hoek, Hans W; van Harten, Peter N ·
Kidney Injury Induced by High-Dose Chaga Mushroom Consumption: Experimental Evidence in a Rat Model.
Lee, Sua; Cui, Sheng; Fang, Xianying; Lee, Hanbi; Lim, Sun Woo; Shin, Yoo Jin; Li, Can; Yang, Chul Woo; Chung, Byung Ha ·
Secondary Oxalate Nephropathy: A Systematic Review.
Lumlertgul, Nuttha; Siribamrungwong, Monchai; Jaber, Bertrand L; Susantitaphong, Paweena ·
The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages.
Taylor, Philip R; Brown, Gordon D; Reid, Delyth M; Willment, Janet A; Martinez-Pomares, Luisa; Gordon, Siamon; Wong, Simon Y C ·
Regulation of the adhesion versus cytotoxic functions of the Mac-1/CR3/alphaMbeta2-integrin glycoprotein.
Ross, Gordon D ·
Function of the lectin domain of Mac-1/complement receptor type 3 (CD11b/CD18) in regulating neutrophil adhesion.
Xia, Yu; Borland, Gillian; Huang, Jun; Mizukami, Isaac F; Petty, Howard R; Todd, Robert F 3rd; Ross, Gordon D ·
C5a-mediated leukotriene B4-amplified neutrophil chemotaxis is essential in tumor immunotherapy facilitated by anti-tumor monoclonal antibody and beta-glucan.
Allendorf, Daniel J; Yan, Jun; Ross, Gordon D; Hansen, Richard D; Baran, Jaroslav T; Subbarao, Kalavathi; Wang, Li; Haribabu, Bodduluri ·
The effects of β-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis.
Rovenský, Jozef; Stančíkova, Maria; Svík, Karol; Bauerová, Katarína; Jurčovičová, Jana ·
Study of new ways of supplementary and combinatory therapy of rheumatoid arthritis with immunomodulators. Glucomannan and Imunoglukán in adjuvant arthritis.
Bauerová, Katarína; Paulovičová, Ema; Mihalová, Danica; Svík, Karol; Ponist, Silvester ·
Gene-edited CRISPR mushroom escapes US regulation.
Waltz, Emily ·
Gene targeting of dikaryotic Pleurotus ostreatus nuclei using the CRISPR/Cas9 system.
Yamasaki, Fuga; Nakazawa, Takehito; Oh, Minji; Bao, Dapeng; Kawauchi, Moriyuki; Sakamoto, Masahiro; Honda, Yoichi ·
Trans-nuclei CRISPR/Cas9: safe approach for genome editing in the edible mushroom excluding foreign DNA sequences.
Koshi, Daishiro; Sugano, Junko; Yamasaki, Fuga; Kawauchi, Moriyuki; Nakazawa, Takehito; Oh, Minji; Honda, Yoichi ·
Simultaneous gene editing of both nuclei in a dikaryotic strain of Ganoderma lucidum using Cas9-gRNA ribonucleoprotein.
Choi, Yeon-Jae; Eom, Hyerang; Nandre, Rutuja; Kim, Minseek; Oh, Youn-Lee; Kim, Sinil; Ro, Hyeon-Su ·
Effect of lentinan on the chemiluminescence produced by human neutrophils and the murine macrophage cell line C4M phi.
Sipka, S; Abel, G; Csongor, J; Chihara, G; Fachet, J ·
Lentinan enhances the antitumor effects of Delta-like 1 via neutrophils.
Xu, Hui; Qi, Zhen; Zhao, Qian; Xue, Jiao; Zhu, Jiahao; He, Yang; Liu, Gang; Qin, Songbing ·
Different activities of antitumor immunomodulators to induce neutrophil adherence response.
Tanaka, Mamoru; Abe, Shigeru ·
Nutritional Profile and Health Benefits of Ganoderma lucidum "Lingzhi, Reishi, or Mannentake" as Functional Foods: Current Scenario and Future Perspectives.
El Sheikha, Aly Farag ·
B vitamins and cardiovascular health: mechanisms, clinical evidence, and precision prevention strategies.
Awashra, Ameer; AbuBaha, Mohammed; Istetieh, Kareem; Sandouka, Dana; Aldwaik, Samia; AbuBaha, Bara; Saife, Sarah; Emara, Ahmed; Zahran, Anwar; Elgendy, Mohamed S; Shubietah, Abdalhakim; Baniowda, Muath A ·
One-carbon metabolism and cardiovascular disease: Molecular mechanisms, genetic influences, and epigenetic regulation.
Al Qassab, Mohamad; Bou Ghanem, Ayman; Hussayni, Yaman; Kadbey, Raghid; Ratel, Yara; Yehya, Shereen; Zahr, Maysaa; Ghadieh, Hilda E; Abi Khattar, Ziad; Azar, Sami; Kanaan, Amjad; Harb, Frederic ·
Ganoderma lucidum mediates microglial polarization and ameliorates experimental autoimmune encephalomyelitis by reducing oxidative stress and inhibiting NF-κB/STAT3 pathway.
Zhang, L; Chen, J; Yuen, S; Wu, M; Li, W; Yan, S; Shen, J ·
Combined Transcriptomic and Metabolomic Analyses of the Response of Ganoderma lucidum to Elevated CO2.
Fang, Tingting; Chen, Lu; Yao, Hui; Li, Ye; Liu, Guohui; Wu, Shaofeng; Lan, Jin; Chen, Xiangdong ·
Activation of serotonin 2A receptors underlies the psilocybin-induced effects on α oscillations, N170 visual-evoked potentials, and visual hallucinations.
Kometer, Michael; Schmidt, André; Jäncke, Lutz; Vollenweider, Franz X ·
Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice.
Hesselgrave, Natalie; Troppoli, Timothy A; Wulff, Andreas B; Cole, Anthony B; Thompson, Scott M ·
Wolves Among Sheep: Sexual Violations in Psychedelic-Assisted Therapy.
Harrison, Tahlia R; Faber, Sonya C; Zare, Manzar; Fontaine, Matthieu; Williams, Monnica T ·
The Perilous Policy of Oregon's Psilocybin Services.
Holoyda, Brian ·
Malpractice and Other Civil Liability in Psychedelic Psychiatry.
Holoyda, Brian James ·
Studying Harms Is Key to Improving Psychedelic-Assisted Therapy-Participants Call for Changes to Research Landscape.
McNamee, Sarah; Devenot, Nese; Buisson, Meaghan ·
Prevalence and predictors of sexual and physical violence during psychedelic use in a US population-based study.
Chwyl, Christina; Ladka, Michael S; Black, Joshua C; Rockhill, Karilynn M; Dart, Richard C; Luoma, Jason B; Monte, Andrew A ·