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Lion's Mane Bioactive Compounds: Hericenones & Erinacines

Explore mushroom research and guides on lion's mane bioactive compounds: hericenones & erinacines.

Lion's Mane Bioactive Compounds: Hericenones & Erinacines

Hericenone C and NGF Synthesis: The Key Mechanism

Hericenone C triggers NGF synthesis via astrocyte cells. Here's how the mechanism works, which hericenone is most potent for NGF, and what changed in 2023.

Lion's Mane Bioactive Compounds: Hericenones & Erinacines

Hericenones A-H: The Lion's Mane Fruiting Body Library

Hericenones A-H: the original geranyl-resorcinol compounds isolated from Lion's Mane fruiting bodies. What the NGF research actually shows, the 2021 structure revision, and 2025 biosynthetic mapping.

Lion's Mane Bioactive Compounds: Hericenones & Erinacines

How Erinacines Cross the Blood-Brain Barrier

Erinacines blood brain barrier: these Lion's Mane diterpenoids cross by passive diffusion. Animal and clinical data confirm brain entry and downstream activity.

Lion's Mane Bioactive Compounds: Hericenones & Erinacines

Isolation and Characterization of Lion's Mane Diterpenoids

Lion's mane erinacines are cyathane diterpenoids (15+ compounds) from mycelium with documented blood-brain barrier crossing. Here's the chemistry, the gene clusters behind their production, and the characterization methods.