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Psilocybin for Smoking Cessation

Explore mushroom research and guides on psilocybin for smoking cessation.

Psilocybin for Smoking Cessation

Psilocybin and Nicotine Addiction: Mechanisms of Action

Research points to three mechanisms for psilocybin's effect on nicotine addiction: identity shift, mystical experience scores, and habit loop disruption.

Psilocybin for Smoking Cessation

Psilocybin for Smoking Cessation vs. Standard Treatments

Psilocybin vs. nicotine patches, varenicline, and bupropion: the 2026 JAMA RCT showed 40.5% vs. 10% abstinence at 6 months, with 60% durability at 30 months.

Psilocybin for Smoking Cessation

Psilocybin for Smoking Cessation: The Johns Hopkins Results

The Johns Hopkins psilocybin smoking cessation studies explained: the 2014 pilot (80% quit rate), 30-month follow-up data, and the 2026 randomized trial.

Psilocybin for Smoking Cessation

Psilocybin Pharmacokinetics: Onset, Peak, and Duration

Clinical plasma data defines when psilocybin kicks in (20-40 min), when psilocin peaks (~2 hours, 17 ng/mL at 25mg), and how long effects last (5.5-6.4 hours).

Psilocybin for Smoking Cessation

Psilocybin's 80% Quit Rate: What the Hopkins Data Shows

Johns Hopkins found an 80% quit rate with psilocybin in 2014. Here's what the full evidence, including the 2026 randomized trial, actually shows.