Ergothioneine & Brain / Neurological Health
Explore mushroom research and guides on ergothioneine & brain / neurological health.
Ergothioneine and Brain Health: Neuroprotective Research
A 2025 systematic review of 19 studies found ergothioneine protects the brain via five pathways. Here is what the evidence shows and where gaps remain.
Ergothioneine and Dementia Prevention: Population Studies
The 2025 Hisayama Study followed 1,344 adults for 11 years and linked higher ergothioneine to lower dementia risk. What all the population evidence shows.
Ergothioneine and Parkinson's Disease: Research Review
A 2025 multi-model study found ergothioneine protected dopaminergic neurons across Drosophila, mice, and patient-derived human neurons. Here's the PD evidence.
Ergothioneine and Parkinson's Disease: Singapore Evidence
The NUS research group spent a decade connecting ergothioneine deficiency to neurodegeneration. Here's what their evidence from 2016 to 2025 does — and doesn't — show about Parkinson's.
OCTN1: How Ergothioneine Crosses the Blood-Brain Barrier
OCTN1 (gene: SLC22A4) is the only way ergothioneine enters the brain. Here's how it works, which regions it reaches, and what happens when it's blocked.