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Psilocybin & Stimulant Addiction

Explore mushroom research and guides on psilocybin & stimulant addiction.

Psilocybin & Stimulant Addiction

Can Psilocybin Help Break Cocaine Dependence?

No published trial has tested psilocybin for cocaine addiction. The case rests on tobacco and alcohol results, population data, and neuroplasticity research.

Psilocybin & Stimulant Addiction

Psilocybin and Dopamine Pathways: Implications for Stimulant Addiction

Psilocybin targets serotonin, not dopamine. So why do researchers think it might help cocaine and meth addiction? Here's what the dopamine data actually shows.

Psilocybin & Stimulant Addiction

Psilocybin for Cocaine Addiction: Emerging Research

No completed RCT exists for psilocybin and cocaine use disorder. Here's what the 2025 systematic review, the animal null results, and the UAB trial show.

Psilocybin & Stimulant Addiction

Psilocybin and Stimulant Addiction: Early-Phase Research on Cocaine and Meth

No approved medication exists for cocaine or meth addiction. Here's what the first human meth pilot and the mixed animal model evidence actually show.

Psilocybin & Stimulant Addiction

Psychedelics and Stimulant Use Disorder: Preclinical Evidence

A 2024 rodent study found psilocybin null for cocaine cues. Here's what the preclinical evidence shows about psychedelics and stimulant use disorder.